It all starts in your gut | OlaWell Skip to main content

Love your gut

It all starts in your gut

1/29/2020

Health is "a state of complete physical, mental, and social well-being and not merely the absence of disease" according to the World Health Organization (WHO). It refers not only to the absence of disease but the ability of living a full life [1].

We now know that our health is greatly influenced by the diversity of our gut microbiota and that diet plays a significant role in shaping it [2]. Read more about your gut microbiome in our first article ‘Introduction to the Gut Microbiome’.

Gut microbiome

Figure 1

It has been shown that the consumption of certain foods can induce large changes in existing microbial composition (so-called “microbial shifts”). Furthermore, these bacteria affect host immune and metabolic pathways, with many implications for human health [3].

For example, one study reported that increased levels of Bifidobacterium and Lactobacillus (which are normally found in our gut) resulted from the whey and pea protein extract consumption, while whey additionally decreases the pathogenic bacteria (ones that cause disease) such as Bacteroides fragilis and Clostridium perfringens [3]. Pea protein has also been observed to increase intestinal SCFA’s (short-chain fatty acids) levels, which are considered anti-inflammatory [3, 4]. On the other hand, counts of Bacteroides and Alistipes were noted to increase with consumption of animal-based protein [5].

In case you did not know: the microbiome is the genetic material of all the microbes that live in and on our body [6]. Genetic material is found in all living organisms, from single-celled bacteria to multicellular mammals like you and I (in two forms: deoxyribonucleic acid - DNA and ribonucleic acid - RNA). DNA (in this case bacterial DNA) is the key determinant for gut microbiome analysis by OlaWell. 

To maintain your overall well-being and to discover what is the right food for you, you should test your gut microbiome! Make OlaWell your first choice. Let us analyze your gut microbiome and help you feel better! 

How is this done? We use next-generation sequencing (NGS) technology, the same used in the Human Genome Project, to analyze the entire spectrum of bacteria in your gut. After stool sample collection, the next step is the sequencing of DNA found in that sample (decoding the genetic material). By using NGS technology, the abundance of specific DNA sequences reveals an abundance of specific microbial species found in our gut. Food recommendations provided by OlaWell are based on the best science and references from top journals that prove the correlation between food, gut microbiome, and health. Find out more at www.olawell.com.

 

References:

[1] World Health Organization.

[2]    Doré, J., & Blottière, H. (2015). The influence of diet on the gut microbiota and its consequences for health. Current Opinion in Biotechnology, 32, 195-199. 

[3]    Singh, R. K., Chang, H. W., Yan, D., Lee, K. M., Ucmak, D., Wong, K., ... & Bhutani, T. (2017). Influence of diet on the gut microbiome and implications for human health. Journal of translational medicine, 15(1), 73.

[4]    Kim, C. H., Park, J., & Kim, M. (2014). Gut microbiota-derived short-chain fatty acids, T cells, and inflammation. Immune network, 14(6), 277-288. 

[5]    De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., ... & Lionetti, P. (2010). Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa. Proceedings of the National Academy of Sciences, 107(33), 14691-14696. 

[6]    Ursell, L. K., Metcalf, J. L., Parfrey, L. W., & Knight, R. (2012). Defining the human microbiome. Nutrition reviews, 70(suppl_1), S38-S44.